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Chinese scientist edits twin human baby genes to prevent HIV infection

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A Chinese scientist and professor named Dr. He Jiankui claimed this week that he edited the genes of recently born twin girls while they were embryos. Using a technique called CRISPR-Cas9, the gene responsible for allowing HIV to infect the body was altered to mimic a natural genetic variation in some humans that confers strong resistance to the virus. The father of the babies in the study is HIV positive, a fact which motivated the study and the family’s willingness to take part.

The study’s twins, referred to as “Lulu and Nana”, are said to be in excellent health, and the full details of the corresponding study promised to be provided for public review in the near future. Dr. He, who studied at Rice University in Texas and Stanford University in California, is expected to speak at the Second International Summit on Human Genome Editing in Hong Kong on Wednesday where further evidence may be presented. Thus far, none has been made available, although Dr. He’s previous work is well known to those in the field, giving certain merit to his claims.

The response to Dr. He’s announcement has, thus far, been overwhelmingly negative along with the validity of the claims being questioned. The ethics of gene editing in babies is decidedly set against the practice in the global scientific community, and a significant number of organizations have issued public statements strongly condemning the professor’s work. The Chinese government has also since ordered an inquiry. While an explicit ban on gene editing on embryos intended for reproduction does not exist in the country, strict ethical guidelines recommend strongly against the practice.

Dr. He in his video announcement of the gene edited twins. | Credit: The He Lab

Additionally, Dr. He adamantly denies that his research and work in gene editing serves the purpose of the infamous “designer baby” concept. “For forty years, regulations and morals have developed together with IVF [and gene editing is another] advancement…only meant to help a small number of families,” he stated in his video published November 25th. In an interview with the AP, he defined his goal as bestowing traits that resist future infections from diseases like HIV, the AIDS virus.

The process involved in editing the twin girls’ DNA, as described, began as a regular In Vitro Fertilization (IVF) process wherein the mother’s eggs were fertilized by the father’s sperm to create an embryo in a laboratory environment. At that stage, a CRISPR/Cas9 protein with gene editing instructions was introduced to amend the embryo DNA, and those embryos were subsequently implanted in the mother. Dr. He has claimed that the resulting genomes were assessed at the embryonic stage, during pregnancy, and after birth to confirm that the intended gene alone was changed.

A visual representation of CRISPR-Cas9 gene editing. | Credit: NIH

The hospital claimed to have approved Dr. He’s research, Shenzhen Harmonicare Women’s and Children’s Hospital, has denied having a relationship with Dr. He or any involvement in the experiment. They have also lodged a police report in this regard. Additionally, Southern University of Science and Technology, the university where Dr. He is employed, stated that the professor has been on unpaid leave since February 1, 2018, thus the research involved with the twins was not affiliated with the school.

One of the primary concerns with editing genomes at the embryo level is the long-term impact on both the humans in question and their offspring who will inherit the modified genes. The edited DNA would eventually enter the general population as it passed on through generations. In this study, CCR5, a gene used to make a protein HIV needs to enter cells, was disabled in the twins’ DNA, an edit which effectively shuts off the “gateway” through which the virus infects the body. Although no unintended consequences have yet been observed in this example, scientists overall point to years of study still needed before clinical treatment can ethically be conducted.

One of the ethical guidelines involved in gene editing is restricting its use to only addressing medical needs which cannot be effectively treated through other means. In denouncing the driver of Dr. He’s study, specifically in addressing HIV via gene editing, safe-sex was recommended as a preventative along with current medical treatments in the case of infection by the director of the Oxford Uehiro Centre for Practical Ethics at the University of Oxford. Opposing the opinion of the medical community, however, a recent study by the Sun Yat-Sen University in China found that around 60% of Chinese people have a favorable view of gene editing for disease therapy. Professor He has also pointed to the discrimination faced by Chinese people with HIV as further motivation for his controversial work.

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Watch the below video He Jianjui published announcing the gene surgery:

Accidental computer geek, fascinated by most history and the multiplanetary future on its way. Quite keen on the democratization of space. | It's pronounced day-sha, but I answer to almost any variation thereof.

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Tesla Cybertruck targets job site crews with new Tailgate Utility Track and Bed Gear Box accessory

Tesla launched a $350 tailgate track and a $985 lockable Bed Gear Box for Cybertruck.

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Tesla’s Cybertruck team added two more items to the Tesla Shop, targeting job site crews and owners who use the truck bed for actual work rather than just showing it off. The official Cybertruck X account posted the Tailgate Utility Track and the Bed Gear Box within minutes of each other, part of a five item batch that also included a reflective jacket, a spray paint hat and an updated reflective tee.

The Tailgate Utility Track runs $350 and turns the folded down tailgate into another mounting surface. It’s a single aluminum track with a T-slot for sliding accessories and two L-track attachment points, plus two load stops included in the box. The pitch is straightforward: strap down oversized cargo, like lumber or a cooler, that hangs off the back of the bed without it sliding out mid-drive. It bolts onto the existing tailgate and works on every Cybertruck trim.

The Bed Gear Box costs $985 and is a different kind of accessory. It’s a lockable aluminum storage box, 55.78 inches long, 19.8 inches wide and 7.79 inches tall, that mounts to the bed’s L-track rails and comes with two internal bins for smaller items. According to Tesla, at just over 57 pounds empty, it’s meant to stay in place rather than come in and out with each trip, giving owners a factory-fit alternative to loose totes for tools, recovery gear or emergency supplies. Tesla’s listing notes that Long Range and Dual Motor AWD Cybertrucks need the L-Tracks accessory installed separately before the Gear Box will mount, since L-tracks come standard only on certain configurations.

Tesla Cybertruck bed gear box accessory

Tesla Cybertruck bed gear box accessory

Both accessories lean on the idea Tesla has been building toward since Elon Musk first described the Cybertruck’s third-party attachment strategy at the 2023 shareholder meeting, when he said the truck would ship with mounting points so outside companies, and Tesla itself, could keep adding gear without redesigning the bed. That’s the same L-track backbone underneath the tailgate shield and jumpseats Tesla launched last year, and the off-road armor package that arrived through the same X account in 2025.

Owners looking to round out the rest of the L-track ecosystem, cargo dividers, MOLLE panels, bed racks and similar gear, can find a wider range of options through our Cybertruck accessories collection.

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Elon Musk says he knows how to save Earth for a billion years

Elon Musk says sentient AI satellites launched from the Moon could keep Earth livable forever.

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Elon Musk spent part of his weekend describing a plan to keep the planet livable for roughly a billion years, and it starts with satellites that can think for themselves.

In a post on X, Musk argued that swapping fossil fuels for solar and wind power will not be enough to protect humanity from what he called extremely severe extinction events, the kind that occur roughly every 100 million years. His fix is what he called sentient satellites, or solar-powered satellites, controlled by AI, that would sit in a fixed spot between Earth and the Sun after being launched off the Moon using a giant electromagnetic catapult instead of rockets.

The satellites’ onboard AI would make continuous, small adjustments rather than waiting on human instructions. The mass driver is Musk’s proposed way of getting the raw material there cheaply by using an electromagnetic launch track built on the Moon, where lower gravity and no atmosphere make it far easier to fling cargo into space than it is from Earth.

Musk shared a Grok generated estimate suggesting roughly 5 percent of Florida’s land, or about 1.68 million acres, could face regular flooding by 2070 under a high sea level rise scenario, and said humanity has about 50 years to act before coastal living looks very different than it does today.

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This is not the first time Musk has floated the idea. He raised a similar concept in November, describing a solar powered AI satellite constellation that could make tiny adjustments to incoming sunlight to fine tune Earth’s temperature. Musk has also tied planetary risk to his broader vision at SpaceX, where his compensation package is explicitly linked to establishing a self-sustaining Mars colony, one he has described as an insurance policy against the kind of extinction event he referenced this weekend, and where he has said humans could set foot within five to seven years.

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Police sergeant recounts his Neuralink journey with Elon Musk’s brain chip

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A former Vancouver police sergeant with ALS accounts his journey to become a patient for Elon Musk’s Neuralink wireless brain-computer interface technology.

“I’m texting you from my brain right now.” That was the first message Lee Marten sent after waking up from Neuralink surgery, five hours and one migraine after dozens of threads were stitched into his motor cortex.

Marten, a former Vancouver police sergeant, is one of the first Canadian ALS patients to receive Neuralink’s N1 brain implant, and the 26th recipient overall. He tells his story in a first-person account published by Maclean’s.

Marten recounts how he was a healthy, athletic Vancouver police sergeant until April 2022 when symptoms of muscle twitching and balance loss, were followed by a bad fall that broke his leg. He would eventually be diagnosed with ALS in early 2025 at the age of 47. ALS, also known as Lou Gehrig’s disease, is a fatal neurodegenerative disease that progressively destroys the motor neurons controlling voluntary muscle movement, eventually taking away a patient’s ability to walk, speak, swallow and breathe. There’s no cure, and most patients live two to five years after diagnosis.

He describes the devastation of the diagnosis and how he began preparing for it while connecting with other young ALS patients through a WhatsApp group called Young Guns. Through that group he learned about a Neuralink clinical trial at Toronto Western Hospital and, after a roughly seven-month vetting process (physical assessments, psychiatric evaluation, a final interview with the Neuralink team), was accepted this past April as the trial’s 26th recipient and the first Canadian ALS patient to get the N1 implant. He recounts the May surgery in detail, including the robotic system that stitched 64 threads into his brain, and describes the app, Link, translating his neural signals into cursor control, which he was using within hours of waking up.

Marten walks through what daily use looks like, including weekly “brain training” exercises, a real-time neural-activity display, charging the implant via a beanie-mounted MagSafe charger, and using the implant for emailing, texting, social media, and gaming via a “Magic Box” that connects it to other devices. He also gives brief context on brain-computer interface history and quite candid about Musk, calling him “divisive” but saying he found him “easy to admire.

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The piece closes on a heavier note, with Marten seeking to pursue medical assistance in dying as his symptoms progressed, noting that he’ll be able to communicate his final words to his family through Neuralink rather than facing a silent decline. He expresses hope the data from his case will help future ALS patients, even without a cure in his own lifetime.

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