News
Researchers fold DNA into world’s smallest tic-tac-toe game
Researchers from The Qian Lab at the California Institute of Technology (Caltech) have used DNA folding, also known as DNA origami, to create the world’s tiniest game of tic-tac-toe. Since its creation in 2006 by Paul Rothemund, this technique has opened up the possibility of building “smart” programmable materials on the nanoscale using these self-assembling molecules. By capitalizing on DNA’s inherent tendency to pair with complementary bases that form its building blocks – guanine (G) pairs with cytosine (C) and adenine pairs (A) with thymine (T) – scientists can take a single strand of DNA and mix in smaller pieces that only attach to certain portions of the longer strand, called ‘staples’, pulling the single strand into the desired form. The team at Caltech has advanced this technique by enabling the forms to be changed, or “reprogrammed”, at will, enabling previously programmed DNA to be upgraded if needed. These advancements may help lead the way in areas such as developing DNA computers and the creation of new chemicals.
Over a period of around six days, each turn taking time for the DNA to reassemble, members of the Caltech research team played out the classic tic-tac-toe game, crowning ‘X’ as the winner. There were two techniques used: First, a set of DNA tiles (squares) were assembled to form the board. The tile assembly was accomplished using general folding techniques now common in the field and previously demonstrated on an advanced scale with the team’s Mona Lisa project wherein numerous tiles were assembled into the famous portrait. Second, the technique of ‘displacement’ allowed team members to insert new tiles, programmed with an ‘X’ or ‘O’ shape for a specific place on the board, to kick out the blank tile previously there. The full details of their accomplishment were published in the December 18, 2018 edition of the journal Nature Communications.
While DNA is generally known to contain the genetic instructions for building living things, as a molecule, it makes a useful tool for building tiny objects. The original shapes formed with the origami technique were 2D – smiley faces, stars, etc. However, in recent years, scientists have moved into increasingly complex 3D shapes – boxes, triangles, and even rabbits. The Qian Lab has additionally developed software that enables other scientists to easily program 2D assemblies from an image using the fractal methods demonstrated in the Mona Lisa project. The protocols output by the software can even be read by lab robots, completing the automation circle.
An animation of the Caltech team’s tic-tac-toe game:
One of the other long-term goals of DNA origami is to develop DNA robots or machines that can be programmed to act in specific ways inside the body. For example, a drug intended to kill cancerous tumor cells could be encapsulated in a DNA-folded box and only opened when tumor cell DNA matched its sequence-based lock. Combining the developments in artificial intelligence for identifying and predicting disease with the potential targeted delivery systems demonstrated with DNA origami, the future of technology in medicine is promising.
Watch the below video by Nature for an overview of the DNA folding process:
Elon Musk
Brazil Supreme Court orders Elon Musk and X investigation closed
The decision was issued by Supreme Court Justice Alexandre de Moraes following a recommendation from Brazil’s Prosecutor-General Paulo Gonet.
Brazil’s Supreme Federal Court has ordered the closure of an investigation involving Elon Musk and social media platform X. The inquiry had been pending for about two years and examined whether the platform was used to coordinate attacks against members of the judiciary.
The decision was issued by Supreme Court Justice Alexandre de Moraes following a recommendation from Brazil’s Prosecutor-General Paulo Gonet.
According to a report from Agencia Brasil, the investigation conducted by the Federal Police did not find evidence that X deliberately attempted to attack the judiciary or circumvent court orders.
Prosecutor-General Paulo Gonet concluded that the irregularities identified during the probe did not indicate fraudulent intent.
Justice Moraes accepted the prosecutor’s recommendation and ruled that the investigation should be closed. Under the ruling, the case will remain closed unless new evidence emerges.
The inquiry stemmed from concerns that content on X may have enabled online attacks against Supreme Court justices or violated rulings requiring the suspension of certain accounts under investigation.
Justice Moraes had previously taken several enforcement actions related to the platform during the broader dispute involving social media regulation in Brazil.
These included ordering a nationwide block of the platform, freezing Starlink accounts, and imposing fines on X totaling about $5.2 million. Authorities also froze financial assets linked to X and SpaceX through Starlink to collect unpaid penalties and seized roughly $3.3 million from the companies’ accounts.
Moraes also imposed daily fines of up to R$5 million, about $920,000, for alleged evasion of the X ban and established penalties of R$50,000 per day for VPN users who attempted to bypass the restriction.
Brazil remains an important market for X, with roughly 17 million users, making it one of the platform’s larger user bases globally.
The country is also a major market for Starlink, SpaceX’s satellite internet service, which has surpassed one million subscribers in Brazil.
Elon Musk
FCC chair criticizes Amazon over opposition to SpaceX satellite plan
Carr made the remarks in a post on social media platform X.
U.S. Federal Communications Commission (FCC) Chairman Brendan Carr criticized Amazon after the company opposed SpaceX’s proposal to launch a large satellite constellation that could function as an orbital data center network.
Carr made the remarks in a post on social media platform X.
Amazon recently urged the FCC to reject SpaceX’s application to deploy a constellation of up to 1 million low Earth orbit satellites that could serve as artificial intelligence data centers in space.
The company described the proposal as a “lofty ambition rather than a real plan,” arguing that SpaceX had not provided sufficient details about how the system would operate.
Carr responded by pointing to Amazon’s own satellite deployment progress.
“Amazon should focus on the fact that it will fall roughly 1,000 satellites short of meeting its upcoming deployment milestone, rather than spending their time and resources filing petitions against companies that are putting thousands of satellites in orbit,” Carr wrote on X.
Amazon has declined to comment on the statement.
Amazon has been working to deploy its Project Kuiper satellite network, which is intended to compete with SpaceX’s Starlink service. The company has invested more than $10 billion in the program and has launched more than 200 satellites since April of last year.
Amazon has also asked the FCC for a 24-month extension, until July 2028, to meet a requirement to deploy roughly 1,600 satellites by July 2026, as noted in a CNBC report.
SpaceX’s Starlink network currently has nearly 10,000 satellites in orbit and serves roughly 10 million customers. The FCC has also authorized SpaceX to deploy 7,500 additional satellites as the company continues expanding its global satellite internet network.
Energy
Tesla Energy gains UK license to sell electricity to homes and businesses
The license was granted to Tesla Energy Ventures Ltd. by UK energy regulator Ofgem after a seven-month review process.
Tesla Energy has received a license to supply electricity in the United Kingdom, opening the door for the company to serve homes and businesses in the country.
The license was granted to Tesla Energy Ventures Ltd. by UK energy regulator Ofgem after a seven-month review process.
According to Ofgem, the license took effect at 6 p.m. local time on Wednesday and applies to Great Britain.
The approval allows Tesla’s energy business to sell electricity directly to customers in the region, as noted in a Bloomberg News report.
Tesla has already expanded similar services in the United States. In Texas, the company offers electricity plans that allow Tesla owners to charge their vehicles at a lower cost while also feeding excess electricity back into the grid.
Tesla already has a sizable presence in the UK market. According to price comparison website U-switch, there are more than 250,000 Tesla electric vehicles in the country and thousands of Tesla home energy storage systems.
Ofgem also noted that Tesla Motors Ltd., a separate entity incorporated in England and Wales, received an electricity generation license in June 2020.
The new UK license arrives as Tesla continues expanding its global energy business.
Last year, Tesla Energy retained the top position in the global battery energy storage system (BESS) integrator market for the second consecutive year. According to Wood Mackenzie’s latest rankings, Tesla held about 15% of global market share in 2024.
The company also maintained a dominant position in North America, where it captured roughly 39% market share in the region.
At the same time, competition in the energy storage sector is increasing. Chinese companies such as Sungrow have been expanding their presence globally, particularly in Europe.
Brazil Supreme Court orders Elon Musk and X investigation closed
FCC chair criticizes Amazon over opposition to SpaceX satellite plan
