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US military uses genetic engineering to develop “living tripwires” for submarines

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The US Department of Defense (DoD) is investing $45 million dollars in a tri-service effort that focuses on synthetic biology (SynBio) for use in military technologies. This interdisciplinary scientific field primarily involves altering the genetic makeup of organisms to achieve specific behavior, and the military wants in on its potential applications. By uniting SynBio experts within the US Air Force, Army, and Navy, DoD officials hope to develop serious capabilities for use throughout the military’s branches.

The long form name of this project is the Applied Research for the Advancement of Science and Technology Priorities Program on Synthetic Biology for Military Environments, and the mission is obvious from its title alone. While still in the early research stages, engineering organisms could provide numerous tools with direct defense applications.

For example, organisms engineered to change their colors based on their environment could be used as living camouflage, and medications infused with protective microbes could help service member survival in tough conditions. However, it’s perhaps the US Naval Research Laboratory (NRL) in Washington DC that may hold the relevant interest in developing SynBio capabilities due to the marine environment potentials it holds.

The USS America arrives at Joint Base Pearl Harbor-Hickam, Hawaii. Ships like these require regular maintenance paint that consumes billions of dollars per year from the DoD budget. | Credit: US Department of Defense

Above the water, engineered self-repairing organisms could spell out self-healing paint for ships and aircraft carriers, cutting billions from the US Navy’s fleet maintenance costs. Even more important for defense needs, though, are the modified organisms that could help the branch’s deep water operations, i.e., submarines. By modifying the environmental response of naturally present organisms, naval defense could have a new type of radar at their disposal.

An abundant seawater-native bacteria with “clinging” properties called Marinobacter is a prime candidate for the DoD’s purposes. Specifically, the organism could be genetically engineered to react to certain types of molecules that aren’t naturally occurring in the ocean, such as diesel fuel or human DNA, and then spread into targeted environments for monitoring. This reaction could perhaps be the release of an electron, thus creating an electrical signal which nearby drones could pick up and transmit where necessary. The ability to detect non-friendly submarines is the key capability the researchers are aiming to achieve, the bacteria acting as “living tripwires.”

The field of synthetic biology is not new in the civilian world. In fact, consumer products currently exist based on it, such as bio fuels, soaps, cleaners, food additives, and a variety of industrial and manufacturing products. One of the challenges of bringing this type of technology to the field for military use is making the modified organisms tough enough to endure the environments needed.

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“If you want to move a biological bio-based sensor to the field you try to ruggedize those organisms. You try to protect them…[and]…increase their longevity in these harsh environments,” explained Dimitra Stratis-Cullum, the lead of U.S. Army Research Laboratory biomaterials team, in a recent forum hosted by the Johns Hopkins University Applied Physics Laboratory.

The current genetic research being conducted in SynBio has demonstrated that the genes of E. coli bacteria can be manipulated to express properties relevant to the larger goal of underwater sensing. However, the significant differences between the E. Coli and the types of organisms natural to deep water environments, such as Marinobacter, can be compared to the differences between mice and humans.

The initial point really is to either prove that the desired outcome is possible or collect data to assist in that effort. In other words, there’s still a lot of work to be done, but making the effort a priority, such as what the Navy’s done with its “Task Force Ocean” mission aimed at strengthening partnerships within academia and the private sector regarding Navy-relevant ocean science, is a focused step in the right direction for the military to achieve its goals in SynBio.

Accidental computer geek, fascinated by most history and the multiplanetary future on its way. Quite keen on the democratization of space. | It's pronounced day-sha, but I answer to almost any variation thereof.

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SpaceX issues statement on Starship V3 Booster 18 anomaly

The incident unfolded during gas-system pressure testing at the company’s Massey facility in Starbase, Texas. 

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Credit: SpaceX/X

SpaceX has issued an initial statement about Starship Booster 18’s anomaly early Friday. The incident unfolded during gas-system pressure testing at the company’s Massey facility in Starbase, Texas. 

SpaceX’s initial comment

As per SpaceX in a post on its official account on social media platform X, Booster 18 was undergoing gas system pressure tests when the anomaly happened. Despite the nature of the incident, the company emphasized that no propellant was loaded, no engines were installed, and personnel were kept at a safe distance from the booster, resulting in zero injuries.

“Booster 18 suffered an anomaly during gas system pressure testing that we were conducting in advance of structural proof testing. No propellant was on the vehicle, and engines were not yet installed. The teams need time to investigate before we are confident of the cause. No one was injured as we maintain a safe distance for personnel during this type of testing. The site remains clear and we are working plans to safely reenter the site,” SpaceX wrote in its post on X. 

Incident and aftermath

Livestream footage from LabPadre showed Booster 18’s lower half crumpling around the liquid oxygen tank area at approximately 4:04 a.m. CT. Subsequent images posted by on-site observers revealed extensive deformation across the booster’s lower structure. Needless to say, spaceflight observers have noted that Booster 18 would likely be a complete loss due to its anomaly.

Booster 18 had rolled out only a day earlier and was one of the first vehicles in the Starship V3 program. The V3 series incorporates structural reinforcements and reliability upgrades intended to prepare Starship for rapid-reuse testing and eventual tower-catch operations. Elon Musk has been optimistic about Starship V3, previously noting on X that the spacecraft might be able to complete initial missions to Mars.

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Tesla analyst maintains $500 PT, says FSD drives better than humans now

The team also met with Tesla leaders for more than an hour to discuss autonomy, chip development, and upcoming deployment plans.

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Credit: Tesla

Tesla (NASDAQ:TSLA) received fresh support from Piper Sandler this week after analysts toured the Fremont Factory and tested the company’s latest Full Self-Driving software. The firm reaffirmed its $500 price target, stating that FSD V14 delivered a notably smooth robotaxi demonstration and may already perform at levels comparable to, if not better than, average human drivers. 

The team also met with Tesla leaders for more than an hour to discuss autonomy, chip development, and upcoming deployment plans.

Analysts highlight autonomy progress

During more than 75 minutes of focused discussions, analysts reportedly focused on FSD v14’s updates. Piper Sandler’s team pointed to meaningful strides in perception, object handling, and overall ride smoothness during the robotaxi demo.

The visit also included discussions on updates to Tesla’s in-house chip initiatives, its Optimus program, and the growth of the company’s battery storage business. Analysts noted that Tesla continues refining cost structures and capital expenditure expectations, which are key elements in future margin recovery, as noted in a Yahoo Finance report. 

Analyst Alexander Potter noted that “we think FSD is a truly impressive product that is (probably) already better at driving than the average American.” This conclusion was strengthened by what he described as a “flawless robotaxi ride to the hotel.”

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Street targets diverge on TSLA

While Piper Sandler stands by its $500 target, it is not the highest estimate on the Street. Wedbush, for one, has a $600 per share price target for TSLA stock.

Other institutions have also weighed in on TSLA stock as of late. HSBC reiterated a Reduce rating with a $131 target, citing a gap between earnings fundamentals and the company’s market value. By contrast, TD Cowen maintained a Buy rating and a $509 target, pointing to strong autonomous driving demonstrations in Austin and the pace of software-driven improvements. 

Stifel analysts also lifted their price target for Tesla to $508 per share over the company’s ongoing robotaxi and FSD programs. 

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SpaceX Starship Version 3 booster crumples in early testing

Photos of the incident’s aftermath suggest that Booster 18 will likely be retired.

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Credit: SpaceX/X

SpaceX’s new Starship first-stage booster, Booster 18, suffered major damage early Friday during its first round of testing in Starbase, Texas, just one day after rolling out of the factory. 

Based on videos of the incident, the lower section of the rocket booster appeared to crumple during a pressurization test. Photos of the incident’s aftermath suggest that Booster 18 will likely be retired. 

Booster test failure

SpaceX began structural and propellant-system verification tests on Booster 18 Thursday night at the Massey’s Test Site, only a few miles from Starbase’s production facilities, as noted in an Ars Technica report. At 4:04 a.m. CT on Friday, a livestream from LabPadre Space captured the booster’s lower half experiencing a sudden destructive event around its liquid oxygen tank section. Post-incident images, shared on X by @StarshipGazer, showed notable deformation in the booster’s lower structure.

Neither SpaceX nor Elon Musk had commented as of Friday morning, but the vehicle’s condition suggests it is likely a complete loss. This is quite unfortunate, as Booster 18 is already part of the Starship V3 program, which includes design fixes and upgrades intended to improve reliability. While SpaceX maintains a rather rapid Starship production line in Starbase, Booster 18 was generally expected to validate the improvements implemented in the V3 program.

Tight deadlines

SpaceX needs Starship boosters and upper stages to begin demonstrating rapid reuse, tower catches, and early operational Starlink missions over the next two years. More critically, NASA’s Artemis program depends on an on-orbit refueling test in the second half of 2026, a requirement for the vehicle’s expected crewed lunar landing around 2028.

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While SpaceX is known for diagnosing failures quickly and returning to testing at unmatched speed, losing the newest-generation booster at the very start of its campaign highlights the immense challenge involved in scaling Starship into a reliable, high-cadence launch system. SpaceX, however, is known for getting things done quickly, so it would not be a surprise if the company manages to figure out what happened to Booster 18 in the near future.

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