Lifestyle
Chinese scientist edits twin human baby genes to prevent HIV infection
A Chinese scientist and professor named Dr. He Jiankui claimed this week that he edited the genes of recently born twin girls while they were embryos. Using a technique called CRISPR-Cas9, the gene responsible for allowing HIV to infect the body was altered to mimic a natural genetic variation in some humans that confers strong resistance to the virus. The father of the babies in the study is HIV positive, a fact which motivated the study and the family’s willingness to take part.
The study’s twins, referred to as “Lulu and Nana”, are said to be in excellent health, and the full details of the corresponding study promised to be provided for public review in the near future. Dr. He, who studied at Rice University in Texas and Stanford University in California, is expected to speak at the Second International Summit on Human Genome Editing in Hong Kong on Wednesday where further evidence may be presented. Thus far, none has been made available, although Dr. He’s previous work is well known to those in the field, giving certain merit to his claims.
The response to Dr. He’s announcement has, thus far, been overwhelmingly negative along with the validity of the claims being questioned. The ethics of gene editing in babies is decidedly set against the practice in the global scientific community, and a significant number of organizations have issued public statements strongly condemning the professor’s work. The Chinese government has also since ordered an inquiry. While an explicit ban on gene editing on embryos intended for reproduction does not exist in the country, strict ethical guidelines recommend strongly against the practice.
Additionally, Dr. He adamantly denies that his research and work in gene editing serves the purpose of the infamous “designer baby” concept. “For forty years, regulations and morals have developed together with IVF [and gene editing is another] advancement…only meant to help a small number of families,” he stated in his video published November 25th. In an interview with the AP, he defined his goal as bestowing traits that resist future infections from diseases like HIV, the AIDS virus.
The process involved in editing the twin girls’ DNA, as described, began as a regular In Vitro Fertilization (IVF) process wherein the mother’s eggs were fertilized by the father’s sperm to create an embryo in a laboratory environment. At that stage, a CRISPR/Cas9 protein with gene editing instructions was introduced to amend the embryo DNA, and those embryos were subsequently implanted in the mother. Dr. He has claimed that the resulting genomes were assessed at the embryonic stage, during pregnancy, and after birth to confirm that the intended gene alone was changed.
The hospital claimed to have approved Dr. He’s research, Shenzhen Harmonicare Women’s and Children’s Hospital, has denied having a relationship with Dr. He or any involvement in the experiment. They have also lodged a police report in this regard. Additionally, Southern University of Science and Technology, the university where Dr. He is employed, stated that the professor has been on unpaid leave since February 1, 2018, thus the research involved with the twins was not affiliated with the school.
One of the primary concerns with editing genomes at the embryo level is the long-term impact on both the humans in question and their offspring who will inherit the modified genes. The edited DNA would eventually enter the general population as it passed on through generations. In this study, CCR5, a gene used to make a protein HIV needs to enter cells, was disabled in the twins’ DNA, an edit which effectively shuts off the “gateway” through which the virus infects the body. Although no unintended consequences have yet been observed in this example, scientists overall point to years of study still needed before clinical treatment can ethically be conducted.
One of the ethical guidelines involved in gene editing is restricting its use to only addressing medical needs which cannot be effectively treated through other means. In denouncing the driver of Dr. He’s study, specifically in addressing HIV via gene editing, safe-sex was recommended as a preventative along with current medical treatments in the case of infection by the director of the Oxford Uehiro Centre for Practical Ethics at the University of Oxford. Opposing the opinion of the medical community, however, a recent study by the Sun Yat-Sen University in China found that around 60% of Chinese people have a favorable view of gene editing for disease therapy. Professor He has also pointed to the discrimination faced by Chinese people with HIV as further motivation for his controversial work.
Watch the below video He Jianjui published announcing the gene surgery:
Lifestyle
Tesla Cybertruck takes a bump from epic failing Dodge Charger
The Cybertruck seemed unharmed by the charging Charger.
There comes a time in a driver’s life when one is faced with one’s limitations. For the driver of a Dodge Charger, this time came when he lost control and crashed into a Tesla Cybertruck–an absolute epic fail.
A video of the rather unfortunate incident was shared on the r/TeslaLounge subreddit.
Charging Charger Fails
As could be seen in the video, which was posted on the subreddit by Model Y owner u/Hammer_of_something, a group of teens in a Dodge Charger decided to do some burnouts at a Tesla Supercharger. Unfortunately, the driver of the Charger failed in his burnout or donut attempt, resulting in the mopar sedan going over a curb and bumping a charging Cybertruck.
Ironically, the Dodge Charger seemed to have been parked at a Supercharger stall before its driver decided to perform the failed stunt. This suggests that the vehicle was likely ICE-ing a charging stall before it had its epic fail moment. Amusingly enough, the subreddit member noted that the Cybertruck did not seem like it took any damage at all despite its bump. The Charger, however, seemed like it ran into some trouble after crashing into the truck.
Alleged Aftermath
As per the the r/TeslaLounge subreddit member, the Cybertruck owner came rushing out to his vehicle after the Dodge Charger crashed into it. The Model Y owner then sent over the full video of the incident, which clearly showed the Charger attempting a burnout, failing, and bumping into the Cybertruck. The Cybertruck owner likely appreciated the video, in part because it showed the driver of the Dodge Charger absolutely freaking out after the incident.
The Cybertruck is not an impregnable vehicle, but it can take bumps pretty well thanks to its thick stainless steel body. Based on this video, it appears that the Cybertruck can even take bumps from a charging Charger, all while chilling and charging at a Supercharger. As for the teens in the Dodge, they likely had to provide a long explanation to authorities after the incident, since the cops were called to the location.
Lifestyle
Anti-Elon Musk group crushes Tesla Model 3 with Sherman tank–with unexpected results
Ironically enough, the group’s video ended up highlighting something very positive for Tesla.
Anti-Elon Musk protesters and critics tend to show their disdain for the CEO in various ways, but a recent video from political action group Led By Donkeys definitely takes the cake when it comes to creativity.
Ironially enough, the group’s video also ended up highlighting something very positive for Tesla.
Tank vs. Tesla
In its video, Led By Donkeys featured Ken Turner, a 98-year-old veteran who served in the British army during World War II. The veteran stated that Elon Musk, the richest man in the world, is “using his immense power to support the far-right in Europe, and his money comes from Tesla cars.”
He also noted that he had a message for the Tesla CEO: “We’ve crushed fascism before and we’ll crush it again.” To emphasize his point, the veteran proceeded to drive a Sherman tank over a blue Tesla Model 3 sedan, which, of course, had a plate that read “Fascism.”
The heavy tank crushed the Model 3’s glass roof and windows, much to the delight of Led By Donkeys’ commenters on its official YouTube channel. But at the end of it all, the aftermath of the anti-Elon Musk demonstration ended up showcasing something positive for the electric vehicle maker.
Tesla Model 3 Tanks the Tank?
As could be seen from the wreckage of the Tesla Model 3 after its Sherman encounter, only the glass roof and windows of the all-electric sedan were crushed. Looking at the wreckage of the Model 3, it seemed like its doors could still be opened, and everything on its lower section looked intact.
Considering that a standard M4 Sherman weighs about 66,800 to 84,000 pounds, the Model 3 actually weathered the tank’s assault really well. Granted, the vehicle’s suspension height before the political action group’s demonstration suggests that the Model 3’s high voltage battery had been removed beforehand. But even if it hadn’t been taken off, it seemed like the vehicle’s battery would have survived the heavy ordeal without much incident.
This was highlighted in comments from users on social media platform X, many of whom noted that a person in the Model 3 could very well have survived the ordeal with the Sherman. And that, ultimately, just speaks to the safety of Tesla’s vehicles. There is a reason why Teslas consistently rank among the safest cars on the road, after all.
Lifestyle
Tesla Model 3 driver is using FSD to travel to Mt. Everest Base Camp
The ambitious, nearly 4,000-kilometer (2,485-mile) Tesla FSD journey is being livestreamed on Chinese social media.
Count on Tesla drivers in China to push Full Self Driving (FSD) as far as it could go. As could be seen in videos posted on Chinese social media, a brave Model 3 owner is currently going on an epic journey from Henan Province to the base camp of Mt. Everest on FSD.
Recent posts from the Model 3 driver suggest that the ambitious destination may be within reach.
Epic FSD Journey
As noted by Tesla owner-enthusiast Aaron Li, the journey from Henan Province to the base camp of Mt. Everest spans almost 4,000 kilometers (2,485 miles). The journey itself is epic, with stunning vistas and roads that require some drivers to bring oxygen canisters with them. The fact that it is being done using FSD makes it extra impressive.
Based on the videos that have been recently shared, the Model 3 running FSD seems to be nearing the Everest Base Camp. There seems to be a good chance that the Tesla Model 3 may reach its destination this Friday.
Previous Everest Trips
This is not the first time that a Tesla has driven to Mt. Everest’s base camp. That would be a Model 3 that was driven in September 2020. That vehicle, which went on a long 5,500 km (3,400-mile) journey, was manually driven to its destination.
In April 2021, Tesla China announced that it has completed the buildout of 11 Supercharger stations in the picturesque route from Chengdu to Tingri. This route would allow drivers to reach the base camp of Mt. Everest. Sure enough, in July 2022, Tesla China shared a video of two Teslas—a Model X and Model Y—reaching the Everest base camp without any issues. Numerous other Tesla drivers have since taken on the long, picturesque journey.
Check out this Tesla Model Y’s journey to the Mt. Everest base camp in the video below.
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